一项基于人群的甲状腺癌与慢性牙周炎的关联的研究

新兴的涉及将牙周炎与一系列癌症联系起来，尤其是甲状腺癌，尽管对这些关联的研究仍处于新生的阶段。 This population-based study aimed to investigate the association of thyroid cancer with chronic periodontitis using Taiwan's Longitudinal Health Insurance Database 2010 (LHID2010).This case-control study utilized LHID2010, selecting 2,775 patients diagnosed with thyroid cancer, matched with 8,325 controls based on age, sex, income, and the presence of diabetes, hypertension, hyperlipidemia, human使用倾向得分匹配的乳头瘤病毒感染和烟草使用障碍。使用多元逻辑回归模型来评估甲状腺癌与慢性牙周炎的关联。一种卡方分析表明，在患有甲状腺癌和对照组的患者之间，慢性牙周炎的患病率显着差异，患有甲状腺癌的患病率分别为38.5％和24.1％，并且分别为24.5％和24.1％。与对照组相比，甲状腺癌患者的先前慢性牙周炎的优势比（OR）为1.991，95％置信区间（CI）为1.816-2.184，P值小于0.001。性别之间的关联相似，调整后的ORS为1.991（95％CI = 1.816〜2.184）男性和1.962（95％CI = 1.765-2.182）的统计学症状较高的男性和女性患者的持续时间较高的较高的男性和女性患者的患者的患病率在统计学上具有较高的较高的患者诊断为较高的患者的患者，均表明男性和女性较高的患者患者的统计学范围更高，而较高的男性患者的患者则诊断出了较高的患者。甲状腺癌强调了包括口腔健康的综合健康监测和预防策略的重要性。这项研究旨在探索甲状腺癌与慢性牙周炎之间的联系。使用台湾的2010年纵向健康保险数据库（LHID2010），我们选择了2,775例甲状腺癌患者，并将他们与8,325名没有疾病的人相匹配，该患者基于年龄，性别，收入和其他健康状况，例如糖尿病，高血压，高胆固醇，HPV，HPV感染和吸烟habits。该研究使用统计模型检查甲状腺癌与慢性牙周炎之间的关系。研究结果表明，甲状腺癌患者中有38.5％患有慢性牙周炎，而对照组的24.1％。在甲状腺癌患者中，患有慢性牙周炎的几乎是高的两倍。这种模式对于男人和女人都是一致的。该研究强调了慢性牙周炎与甲状腺癌之间的密切联系，强调提高公众对牙周炎潜在风险的认识的重要性。

Emerging concerns link periodontitis to an array of cancers, notably thyroid cancer, though investigations into these associations are still in the nascent stages. This population-based study aimed to investigate the association of thyroid cancer with chronic periodontitis using Taiwan's Longitudinal Health Insurance Database 2010 (LHID2010).This case-control study utilized LHID2010, selecting 2,775 patients diagnosed with thyroid cancer, matched with 8,325 controls based on age, sex, income, and the presence of diabetes, hypertension, hyperlipidemia, human papillomavirus infection, and tobacco use disorder using propensity-score matching. Multivariate logistic regression models were used to evaluate the association of thyroid cancer with chronic periodontitis.A chi-squared analysis demonstrated a significant disparity in the prevalence of chronic periodontitis between those diagnosed with thyroid cancer and the controls, with prevalence rates of 38.5% and 24.1% respectively, and a p-value less than 0.001. The odds ratio (OR) for having prior chronic periodontitis among patients with thyroid cancer compared to controls was 1.991, with a 95% confidence interval (CI) of 1.816-2.184 and a p-value less than 0.001. The association was similar between sexes, yielding adjusted ORs of 1.991 (95% CI = 1.816∼2.184) for men and 1.962 (95% CI = 1.765-2.182) for women, indicating a statistically significant higher prevalence of chronic periodontitis in both male and female patients diagnosed with thyroid cancer compared to their control counterparts.The findings highlight chronic periodontitis as a potential risk factor for thyroid cancer, underscoring the importance of integrated health surveillance and preventive strategies that encompass oral health.This study aimed to explore the link between thyroid cancer and chronic periodontitis. Using Taiwan's Longitudinal Health Insurance Database 2010 (LHID2010), we selected 2,775 patients with thyroid cancer and matched them with 8,325 individuals without the disease based on age, sex, income, and other health conditions such as diabetes, hypertension, high cholesterol, HPV infection, and smoking habits. The study used statistical models to examine the relationship between thyroid cancer and chronic periodontitis. The findings showed that 38.5% of thyroid cancer patients had chronic periodontitis, compared to 24.1% of the control group. The odds of having chronic periodontitis were nearly twice as high in thyroid cancer patients. This pattern was consistent for both men and women. The study underscores the strong connection between chronic periodontitis and thyroid cancer, emphasizing the importance of raising public awareness about the potential risks of periodontitis.