在电子废物附近生长的食用蔬菜：对消费者潜在健康风险和DNA损害的研究
Edible vegetables grown in the vicinity of electronic wastes: A study of potential health risks and DNA damage in consumers
影响因子:4.60000
分区:医学3区 / 药学2区 毒理学2区
发表日期:2024 Dec
作者:
Okunola A Alabi
摘要
人们对垃圾场附近/ON/范围内的可食用植物的健康效应越来越关注。这项研究调查了两种可食用的蔬菜：在尼日利亚一个主要的非正式垃圾场附近生长的杂种杂种和三角形（JACQ）。测量了蔬菜中多芳烃（PAHS），多氯联苯（PCB），多溴二苯基醚（PBDE）和重金属浓度的水平。使用危害指数（HI），终生癌症风险（LCR），估计的每日摄入量（EDI）和危害商（HQ）评估食用蔬菜的健康风险。使用对鼠伤寒沙门氏菌（TA100和TA98）的AMES沙门氏菌波动测试以及对大肠杆菌（PQ37）的SOS Chromo测试，评估了蔬菜的致命性和遗传毒性。两种蔬菜的重金属，PBDE，PCB和有害PAH的水平升高。与杂曲曲霉相比，T。t。triangulare被更污染。蔬菜中有机成分和重金属的数量有利。总部，HI和LCR的水平高于建议的指南值，表明致癌和非致癌性后果均具有显着风险，尤其是在儿童中。在AMES测试中，这两种蔬菜即使以50％的浓度为诱变。 SOS-Chromo测试结果证实了这一点，表明两种蔬菜确实是遗传毒性。这项研究表明，种植在垃圾场附近的粮食作物的有害影响。因此，应采取足够的措施，以阻止农民和个人从施肥中使用垃圾场或在过去或现在被用作垃圾的土壤中种植。
Abstract
There has been a growing concern on the health effect of edible plants growing near/on/within the vicinity of dumpsites. This study investigated two edible vegetables: Amarathus hybridus and Talinum triangulare (Jacq) grown in the vicinity of a major informal dumpsite of electronic waste in Nigeria. The levels of polyaromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), and heavy metal concentrations in the vegetables were measured. The health risks of consuming the vegetables were assessed using the hazard index (HI), lifetime cancer risk (LCR), estimated daily intake (EDI), and hazard quotient (HQ). Using the Ames Salmonella fluctuation test on Salmonella typhimurium (TA100 and TA98) and the SOS chromo test on Escherichia coli (PQ37), the mutagenicity and genotoxicity of the vegetables were evaluated. The two vegetables have elevated levels of heavy metals, PBDEs, PCBs, and hazardous PAHs. Compared to A. hybridus, T. triangulare was more contaminated. The amounts of organic constituents and heavy metals in the vegetables correlated favorably. The levels of the HQ, HI, and LCR were above the suggested guideline values, indicating a significant risk of both carcinogenic and non-carcinogenic consequences, particularly in children. The two vegetables were mutagenic even at 50 % concentration in the Ames test. This was corroborated with SOS-chromo test results showing that the two vegetables were indeed genotoxic. This study demonstrated the harmful effects of growing food crops close to dumpsites; therefore, sufficient measures should be implemented to stop farmers and individuals from utilizing dirt from dumps as fertilizer or from planting in soil that has been used as a dump in the past or present.