中期因子将衰老与乳腺癌联系起来——癌症风险的新预测因子。
Midkine links aging with breast cancer-A new predictor of cancer risk.
发表日期：2024 Sep 30
作者：
Jane E Visvader
来源：
CANCER CELL
摘要：
尽管衰老是癌症最严重的危险因素之一，但人们对促进肿瘤发生的生物学机制知之甚少。在本期《癌细胞》中，Yan 等人。解决了乳腺癌背景下的这一基本问题，并报告了中期因子在衰老过程中上调并可促进肿瘤发生。版权所有 © 2024 Elsevier Inc. 保留所有权利。
Despite aging being one of the strongest risk factors for cancer, little is known about the biological mechanisms that promote tumor initiation. In this issue of Cancer Cell, Yan et al. address this fundamental question in the context of breast cancer and report that midkine is upregulated during the aging process and can promote tumorigenesis.Copyright © 2024 Elsevier Inc. All rights reserved.