我们的目的是报告老年人（年龄≥65岁）脑静脉血栓（CVT）的特征。这个多中心回顾性队列包括2011年至2021年间在巴黎大区九家医院因首次CVT住院的老年患者。将估计的发病率与法国健康保险数据系统记录的 CVT 进行比较。 Lariboisière 医院的 CVT 登记处允许将我们的老年队列与 65 岁以下的个体进行比较。这项研究纳入了 114 名患者（平均年龄 = 74.2 岁，范围 = 65-93，61%为女性）。法兰西岛地区老年人 CVT 年发病率为每百万老年人 5.9-7.1 例，而全国范围内为每百万老年人 8.5 例。头痛和局灶性功能障碍是最常见的初始临床特征（分别为 50% 和 51%），其次是癫痫发作和精神错乱（40% 和 27%）。治疗包括抗凝治疗（93%），以及罕见的血管内手术（2%）或颅骨切除术（1%）。与年龄 <65 岁的成年患者（年轻成人）相比，老年患者的头痛（50% vs. 96%，p<0.01）和颅内高压（7% vs. 22%，p<0.01）较少，但癫痫发作和局灶性发作较多赤字（分别为 40% vs. 27% 和 51% vs. 38%，p < 0.01）。老年患者的潜在癌症、血液病和局部感染比年轻人更常见 (p<0.01)。我们的老年队列患者的预后比年轻人差； 8% 在急性期死亡，73% 在 1 年时获得良好转归（分别为 1.7% 和 87%，p<0.01）。老年患者 CVT 具有特定的临床表现、流行病学和危险因素，例如如癌症或血液病，需要专门的治疗。© 2024 作者。约翰·威利出版的《欧洲神经病学杂志》

We aimed to report the characteristics of cerebral venous thrombosis (CVT) in elderly people (aged ≥65 years).This multicenter retrospective cohort included elderly patients hospitalized for a first CVT in nine Paris-Ile-de-France hospitals between 2011 and 2021. The estimated incidence was compared to CVT recorded by the French health insurance data system. Lariboisière Hospital's CVT registry allowed comparisons of our elderly cohort with individuals younger than 65 years.One hundred fourteen patients were included in this study (mean age = 74.2 years, range = 65-93, 61% female). The CVT annual incidence in Ile-de-France was 5.9-7.1 per million elderly individuals versus 8.5 per million nationwide. Headaches and focal deficits were the most common initial clinical features (50% and 51%, respectively), followed by seizures and confusion (40% and 27%). Treatment included anticoagulation (93%) and, rarely, endovascular procedure (2%) or craniectomy (1%). Compared with adult patients aged <65 years (younger adults), elderly patients presented fewer headaches (50% vs. 96%, p < 0.01) and intracranial hypertension (7% vs. 22%, p < 0.01) but more seizures and focal deficits (40% vs. 27% and 51% vs. 38%, respectively, p < 0.01). Underlying cancer, hemopathy, and locoregional infections were more frequent in elderly patients than among younger adults (p < 0.01). The prognosis of patients from our elderly cohort was poorer than that of younger adults; 8% died in the acute phase, and 73% had a favorable outcome at 1 year (vs. 1.7% and 87%, respectively, p < 0.01).CVT in elderly patients has a specific clinical presentation, epidemiology, and risk factors such as cancer or hemopathy, justifying specialized management.© 2024 The Author(s). European Journal of Neurology published by John Wiley & Sons Ltd on behalf of European Academy of Neurology.