肺部肿块是超声内镜 (EUS) 组织采集领域的诊断挑战，特别是通过经食管 EUS-FNB（细针活检）。我们的研究评估了 EUS-FNB 治疗肺部病变的可行性、诊断性能和安全性。前瞻性登记纳入了 53 名患者。所有 EUS 程序均由经验丰富的超声内镜医师执行。结果为标本充分性、诊断准确性、诊断敏感性、诊断特异性和安全性。平均年龄为 70±10.4 岁，71.7% 为男性。病灶平均大小为52.4±23.3 mm，患者多为单一病灶（86.8%）。大多数患者诊断时已处于晚期（IV期，41.82％），最常见的肺癌是非小细胞肺癌（69.4％）。诊断充分率为92.86%，诊断准确率为87.5%。 3 次手术中报告了不良事件。经食管 EUS-FNB 是一种可行且安全的诊断方法，可通过 EUS 进行肺部肿块组织取样。版权所有 © 2024 美国胃肠内窥镜协会。由爱思唯尔公司出版。保留所有权利。

Pulmonary masses are a diagnostic challenge in the field of endoscopic ultrasound(EUS) tissue acquisition, especially through transesophageal EUS-FNB(fine needle biopsy). Our study evaluated the feasibility, diagnostic performance, and safety of EUS-FNB of pulmonary lesions.Fifty-three patients were enrolled in a prospective registry. All of the EUS procedures were performed by experienced endosonographers. Outcomes were specimen adequacy, diagnostic accuracy, diagnostic sensibility, diagnostic specificity, and safety.The mean age was 70±10.4, and 71.7% were male. The mean lesion size was 52.4±23.3 mm, and patients had mostly a single lesion(86.8%). Most of the patients had advanced stage at diagnosis(stage IV, 41.82%), and the most common lung cancer was non-small cell lung carcinoma(69.4%). Diagnostic adequacy rate was 92.86%, and diagnostic accuracy was 87.5%. Adverse events were reported in 3 procedures.Transesophageal EUS-FNB is a feasible and safe diagnostic method of tissue sampling for lung masses reachable by EUS.Copyright © 2024 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.