EUS引导的过道细节活检对肺肿块的活检抽样：诊断性能和安全性
EUS-guided transesophageal fine-needle biopsy sampling of lung masses: diagnostic performance and safety
影响因子:7.50000
分区:医学1区 Top / 胃肠肝病学2区
发表日期:2025 Feb
作者:
Giacomo Emanuele Maria Rizzo, Mario Traina, Dario Ligresti, Lucio Carrozza, Gabriele Rancatore, Rosa Liotta, Alessandro Bertani, Ilaria Tarantino
摘要
肺部肿块是EUS组织采集领域的诊断挑战，尤其是通过EUS过的EUS指导的细针样本采样（EUS-FNB）。我们的研究评估了肺部病变EUS-FNB的可行性，诊断性能和安全性。五十三名患者被招募到前瞻性注册表中。所有EUS程序均由经验丰富的内感染者进行。结果是标本充足性，诊断准确性，诊断性敏感性，诊断特异性和安全性。平均患者年龄为70±10.4岁，男性为71.7％。平均病变大小为52.4±23.3 mm，患者大多有单个病变（86.8％）。大多数患者在诊断时患有晚期阶段（IV期为41.82％），最常见的肺癌是非小细胞肺癌（69.4％）。诊断充足率为92.86％，诊断准确性为87.5％。在3个程序中报道了不良事件。透射食管EUS-FNB是EUS可到达的肺肿块的可行且安全的诊断方法。
Abstract
Pulmonary masses are a diagnostic challenge in the field of EUS tissue acquisition, especially through transesophageal EUS-guided fine-needle biopsy sampling (EUS-FNB). Our study evaluated the feasibility, diagnostic performance, and safety of EUS-FNB of pulmonary lesions.Fifty-three patients were enrolled in a prospective registry. All EUS procedures were performed by experienced endosonographers. Outcomes were specimen adequacy, diagnostic accuracy, diagnostic sensibility, diagnostic specificity, and safety.The mean patient age was 70 ± 10.4 years, and 71.7% were men. The mean lesion size was 52.4 ± 23.3 mm, and patients mostly had a single lesion (86.8%). Most patients had an advanced stage at diagnosis (stage IV, 41.82%), and the most common lung cancer was non-small cell lung carcinoma (69.4%). The diagnostic adequacy rate was 92.86%, and diagnostic accuracy was 87.5%. Adverse events were reported in 3 procedures.Transesophageal EUS-FNB is a feasible and safe diagnostic method of tissue sampling for lung masses reachable by EUS.