痛苦的现实：导航头颈癌的复杂性
Painful Realities: Navigating the Complexities of Head and Neck Cancer Pain
影响因子:2.90000
分区:医学3区 / 牙科与口腔外科4区
发表日期:2024 Oct 07
作者:
Hayden F Byrd, Zachary A Kohutek
摘要
头颈癌（HNC）及其治疗可能会引起严重的疼痛，从而深刻影响患者的生活质量和治疗结果。了解HNC疼痛的全部范围对于有效的管理和改善患者护理至关重要。该评论旨在全面分析HNC患者所经历的疼痛的多方面性质，包括其各种病因和管理策略。HHNC疼痛可能是由肿瘤程度，治疗相关的毒性或合并症的肿瘤范围引起的。病理生理学涉及伤害性，神经性和炎症机制之间的复杂相互作用。最佳疼痛控制需要使用药理学和非药物疗法采用多模式的患者监管方法。对我们对HNC疼痛的了解并优化其管理对于改善受影响个体的整体健康和治疗结果至关重要。未来的研究应着重于理解详细的疼痛机制，以制定个性化的疼痛管理策略并探索新颖的治疗靶标。通过实施HNC疼痛管理的全面方法，医疗保健提供者可以通过癌症治疗旅程更好地支持患者。
Abstract
Head and neck cancer (HNC) and its treatments can cause significant pain, which can profoundly impact patients' quality of life and treatment outcomes. Understanding the full scope of HNC pain is essential for effective management and improved patient care.This review aims to comprehensively analyze the multifaceted nature of pain experienced by individuals with HNC, including its various etiologies and management strategies.HNC pain can arise from tumor extent, treatment-related toxicity, or comorbid conditions. The pathophysiology involves complex interactions between nociceptive, neuropathic, and inflammatory mechanisms. Optimal pain control requires a multimodal patient-tailored approach utilizing both pharmacological and non-pharmacological therapies.Enhancing our understanding of HNC pain and optimizing its management is imperative for improving the overall well-being and treatment outcomes of affected individuals. Future research should focus on understanding detailed pain mechanisms, with the goal of developing personalized pain management strategies and exploring novel therapeutic targets. By implementing comprehensive approaches to HNC pain management, healthcare providers can better support patients through their cancer treatment journey.