美国中央脑肿瘤登记处 (CBTRUS) 与疾病控制与预防中心和国家癌症研究所合作，是最大的基于人群的登记处，专门关注原发性脑肿瘤和其他中枢神经系统 (CNS) 肿瘤在美国 (US) 并代表整个美国人口。该报告包含有关原发性脑肿瘤的最新的基于人群的数据，并在完整性和准确性方面取代了以前的所有报告。所有比率均根据 2000 名美国标准人口进行年龄调整，并按每 100,000 人计算。 2017年至2021年间，所有原发性恶性和非恶性脑部及其他中枢神经系统肿瘤的平均年龄调整发病率（AAAIR）为每10万人中25.34例（恶性AAAIR = 6.89和非恶性AAAIR = 18.46）。女性的总体比率高于男性（每 10 万人中 28.77 人对 21.78 人），非西班牙裔黑人高于非西班牙裔白人（每 10 万人中 26.60 人对 25.72 人），非西班牙裔美洲印第安人/阿拉斯加原住民（每 10 万人中 23.48 人）。每 100,000 人）、非西班牙裔亚洲人或太平洋岛民（每 100,000 人 19.86 人）以及所有种族的西班牙裔人（每 100,000 人 22.37 人）。胶质瘤占所有肿瘤的22.9%。最常见的脑部和其他中枢神经系统恶性组织病理学是胶质母细胞瘤（占所有肿瘤的 13.9%，占所有恶性肿瘤的 51.5%），最常见的非恶性组织病理学是脑膜瘤（占所有肿瘤的 41.7%，占所有非恶性肿瘤的 56.8%）。 -恶性肿瘤）。胶质母细胞瘤在男性中更常见，脑膜瘤在女性中更常见。在儿童和青少年（0-19岁）中，所有原发性脑肿瘤和其他中枢神经系统肿瘤的发病率为每10万人中有6.02人。 2017年至2021年间，有87,053人死于恶性脑肿瘤和其他中枢神经系统肿瘤。这意味着年平均死亡率为每10万人中4.41人，平均每年有17,411人死亡。诊断出恶性脑部或其他中枢神经系统肿瘤后的五年相对生存率为 35.7%。对于非恶性脑部或其他中枢神经系统肿瘤，五年相对生存率为 92.0%。© 作者 2024。由牛津大学出版社代表神经肿瘤学会出版。版权所有。如需商业重复使用，请联系 reprints@oup.com 获取转载和转载的翻译权。所有其他权限都可以通过我们网站文章页面上的权限链接通过我们的 RightsLink 服务获得 - 如需了解更多信息，请联系journals.permissions@oup.com。

The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with the Centers for Disease Control and Prevention and the National Cancer Institute, is the largest population-based registry focused exclusively on primary brain and other central nervous system (CNS) tumors in the United States (US) and represents the entire US population. This report contains the most up-to-date population-based data on primary brain tumors available and supersedes all previous reports in terms of completeness and accuracy. All rates are age-adjusted using the 2000 US standard population and presented per 100,000 population. Between 2017 and 2021, the average annual age-adjusted incidence rate (AAAIR) of all primary malignant and non-malignant brain and other CNS tumors was 25.34 per 100,000 population (malignant AAAIR=6.89 and non-malignant AAAIR=18.46). This overall rate was higher in females compared to males (28.77 versus 21.78 per 100,000) and non-Hispanic Black persons compared to persons who were non-Hispanic White (26.60 versus 25.72 per 100,000), non-Hispanic American Indian/Alaska Native (23.48 per 100,000), non-Hispanic Asian or Pacific Islander (19.86 per 100,000), and Hispanic persons of all races (22.37 per 100,000). Gliomas accounted for 22.9% of all tumors. The most commonly occurring malignant brain and other CNS histopathology was glioblastoma (13.9% of all tumors and 51.5% of all malignant tumors), and the most common predominantly non-malignant histopathology was meningioma (41.7% of all tumors and 56.8% of all non-malignant tumors). Glioblastomas were more common in males, and meningiomas were more common in females. In children and adolescents (ages 0-19 years), the incidence rate of all primary brain and other CNS tumors was 6.02 per 100,000 population. There were 87,053 deaths attributed to malignant brain and other CNS tumors between 2017 and 2021. This represents an average annual mortality rate of 4.41 per 100,000 population and an average of 17,411 deaths per year. The five-year relative survival rate following diagnosis of a malignant brain or other CNS tumor was 35.7%. For a non-malignant brain or other CNS tumor the five-year relative survival rate was 92.0%.© The Author(s) 2024. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.