体重指数（BMI）和腰围（WC）等传统指标无法准确评估与腹部肥胖相关的健康结果，因为它们忽略了脂肪组织分布的复杂性。值得注意的是，在中国人口统计数据中，身体成分与身高的差异仍未得到充分研究。本研究介绍了使用计算机断层扫描 (CT) 扫描的腹部肥胖身高归一化指数，并进一步评估其与各种健康结果的关联。 在庞大、多样化的中国人群中（n = 1054 名健康个体；n = 1159 名患有血脂异常的人；n = 803 名）患有糖尿病；n = 1289 患有心脑血管疾病；n = 1108 患有癌症；n = 509 患有骨质异常），进行腹部 CT 扫描并使用异速生长模型分析得出身高标准化指数（身体成分/高度β）。 Logistic 回归模型评估了这些指数与健康结果之间的关联。观察到内脏脂肪组织 (VAT)、皮下脂肪组织 (SAT) 和总腹部脂肪组织 (TAT) 以及矢状直径 (SAD) 具有不同的缩放能力，具有明显的性别差异。男性的增值税功效为 1.786±1.270，女性的增值税功效为 1.274±0.692。男性 SAT 的功效为 2.266±0.856，女性为 1.656±0.497。男性的 TAT 功效为 2.141±0.967，女性的 TAT 功效为 1.438±0.489。男性的 SAD 功效为 0.646±0.217，女性的 SAD 功效为 0.678±0.141。在控制年龄后，BMI和WC、VAT/身高β、TAT/身高β和SAD/身高β与健康结果的几率保持显着正相关，而SAT/身高β则不然。我们的研究结果支持了身高标准化指数的临床实用性，特别是健康结果评估中的增值税/身高β、TAT/身高β和SAD/身高β。这些指数以可靠的经验数据为基础，强调了在肥胖相关健康评估中采取细致入微的方法的必要性，提倡偏离 BMI 等传统方法。© 2024 作者。 《恶病质、肌肉减少症和肌肉杂志》由 Wiley periodicals LLC 出版。

Traditional metrics such as body mass index (BMI) and waist circumference (WC) fail to accurately assess the health outcomes associated with abdominal adiposity, because they neglect the intricacies of adipose tissue distribution. Notably, the variability in body composition scaled to height remains underexplored in Chinese demographics. This study introduces height-normalised indices of abdominal adiposity using computed tomography (CT) scans and further assesses their associations with various health outcomes.In a large, diverse Chinese population (n = 1054 healthy individuals; n = 1159 with dyslipidemia; n = 803 with diabetes; n = 1289 with cardio-cerebrovascular diseases; n = 1108 with cancers; and n = 509 with abnormal bone mas), abdominal CT scans were performed and allometric growth model analyses were used to derive height-normalised indices (body composition/heightβ). Logistic regression models assessed the associations between these indices and health outcomes.Distinct scaling powers were observed for visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT) and total abdominal adipose tissue (TAT), as well as for sagittal diameter (SAD), with marked sex differences. Powers for VAT were 1.786 ± 1.270 for males and 1.274 ± 0.692 for females. Powers for SAT were 2.266 ± 0.856 for males and 1.656 ± 0.497 for females. Powers for TAT were 2.141 ± 0.967 for males and 1.438 ± 0.489 for females. Powers for SAD were 0.646 ± 0.217 for males and 0.678 ± 0.141 for females. After controlling for age, BMI and WC, VAT/heightβ, TAT/heightβ and SAD/heightβ retained their significantly positive associations with the odds of health outcomes, whereas SAT/heightβ did not.Our findings endorse the clinical utility of height-normalised indices, particularly VAT/heightβ, TAT/heightβ and SAD/heightβ, in health outcomes assessment. These indices, grounded in robust empirical data, underscore the necessity of a nuanced approach in obesity-related health evaluations, advocating for a departure from conventional methods like BMI.© 2024 The Author(s). Journal of Cachexia, Sarcopenia and Muscle published by Wiley Periodicals LLC.