尽管人乳头瘤病毒 (HPV) 疫苗接种率不断增加，但美国新诊断宫颈癌的年龄调整率仍保持稳定。众所周知，社会人口因素会导致宫颈癌护理不平等，因此我们旨在评估其对成人 HPV 疫苗接种率追赶的影响。“我们所有人 (AoU) 研究计划”是一项由美国国立卫生研究院赞助的纵向队列研究。健康。 2018 年 5 月至 2023 年 4 月期间登记的所有年龄 18-47 岁、出生时性别为女性的参与者均纳入本次分析。主要结果是接受 HPV 疫苗接种。使用双变量和多变量测试来检验关联性。 AoU 计划总共确定了 113,344 名参与者，其中 53% (n = 60,594) 自我认定为少数种族或族裔。据记录，只有 3575 名参与者 (3.2%) 接种了 HPV 疫苗。接种疫苗的中位年龄为 26 岁，18-27 岁的参与者更有可能接种疫苗。没有健康保险的参与者（OR = 0.32，95% CI 0.26-0.40）、稳定就业（OR = 0.85，95% CI 0.79-0.91）以及收入较低的参与者（OR = 0.87，95% CI 0.79-0.97）接受 HPV 疫苗接种的可能性显着降低。将费用描述为医疗保健障碍的参与者也不太可能接受 HPV 疫苗接种（OR = 0.82，95% CI 0.73-0.93）。包括低收入、缺乏健康保险和缺乏稳定就业在内的社会人口因素都与此相关居住在美国的成年女性接种 HPV 疫苗的可能性较低。版权所有 © 2024。由 Elsevier Inc. 出版。

Age-adjusted rates of new cervical cancer diagnoses in the United States have remained stable despite increasing availability of Human Papilloma Virus (HPV) vaccination. As it is well established that sociodemographic factors drive cervical cancer care inequity, we aimed to evaluate their impact on catch-up HPV vaccination rates in adults.The All of Us (AoU) Research Program is a longitudinal cohort study sponsored by the National Institutes of Health. All participants ages 18-47 assigned female sex at birth enrolled between May 2018 and April 2023 were included in this analysis. Primary outcome was receipt of HPV vaccination. Bivariable and multivariable tests were used to examine associations.A total of 113,344 participants were identified in the AoU program, with 53 % (n = 60,594) self-identifying as a racial or ethnic minority. Only 3575 participants (3.2 %) were documented as having received HPV vaccination. Median age of vaccination was 26 and participants ages 18-27 were more likely to be vaccinated. Participants without health insurance (OR = 0.32, 95 % CI 0.26-0.40), stable employment (OR = 0.85, 95 % CI 0.79-0.91), and those who reported lower income (OR = 0.87, 95 % CI 0.79-0.97) were significantly less likely to have received HPV vaccination. Participants who described cost as a barrier to healthcare were also less likely to have received HPV vaccination (OR = 0.82, 95 % CI 0.73-0.93).Sociodemographic factors including low income, lack of health insurance, and lack of stable employment were all associated with lower likelihood of catch-up HPV vaccination among adult women living in the United States.Copyright © 2024. Published by Elsevier Inc.