许多儿童癌症幸存者面临心血管疾病和中风的风险。北美儿童肿瘤学组长期随访指南建议癌症幸存者在颈部放射治疗 (RT) ≥40 Gy 10 年后进行颈动脉超声检查。尚未描述颈动脉超声在这一人群中的应用。 1970-1999 年诊断的儿童癌症幸存者 (N = 8693) 和参加儿童癌症幸存者研究的兄弟姐妹 (N = 1989) 被问及是否曾经接受过颈动脉超声检查。评估了颈动脉超声的患病率。在多变量泊松回归模型中评估患病率 (PR) 和 95% 置信区间 (CI)。在没有报告心血管疾病的参与者中，颈部 RT ≥ 40 Gy 的幸存者 (N = 172) 的颈动脉超声患病率是 29.7 %（95% CI，22.5-36.8），显着高于 <40 Gy 的患者（患病率 10.7%；95% CI，9.9%-11.4%）。无心血管疾病的兄弟姐妹 (N = 1621) 颈动脉超声检查患病率最低 (4.7%; 95% CI, 3.6%-5.7%)。在未报告心血管疾病且颈部放疗≥40 Gy 的幸存者的多变量模型中，随访时年龄超过 50 岁（对比 18-49）的幸存者（PR = 1.82；95% CI，1.09-3.05） ，在过去 2 年内曾看过癌症专家的病史 (PR = 2.58; 95% CI, 1.53-4.33)，或做过结肠镜检查 (PR = 2.02; 95% CI, 1.17-3.48) 或超声心动图 (PR = 6.42；95% CI，1.54-26.85）更有可能进行颈动脉超声检查。尽管符合现有指南，许多幸存者并未接受颈动脉超声检查。相关的医疗保健服务特征，例如看过癌症专家或进行其他测试。© 2024 美国癌症协会。

Many childhood cancer survivors are at risk for cardiovascular disease and stroke. The North American Children's Oncology Group long-term follow-up guidelines recommend carotid ultrasound in cancer survivors 10 years after neck radiation therapy (RT) ≥40 Gy. The use of carotid ultrasound in this population has not been described.Survivors of childhood cancer diagnosed 1970-1999 (N = 8693) and siblings (N = 1989) enrolled in the Childhood Cancer Survivor Study were asked if they had ever had a carotid ultrasound. Prevalence of carotid ultrasound was evaluated. Prevalence ratios (PR) and 95% confidence intervals (CIs) were evaluated in multivariate Poisson regression models.Among participants with no reported cardiovascular condition, prevalence of carotid ultrasound among survivors with RT ≥40 Gy to the neck (N = 172) was 29.7% (95% CI, 22.5-36.8), significantly higher than those with <40 Gy (prevalence 10.7%; 95% CI, 9.9%-11.4%). Siblings without a cardiovascular condition (N = 1621) had the lowest prevalence of carotid ultrasound (4.7%; 95% CI, 3.6%-5.7%). In a multivariable models among survivors with no reported cardiovascular condition and RT ≥40 Gy to the neck, those who were over age 50 (vs. 18-49) at follow-up (PR = 1.82; 95% CI, 1.09-3.05), with a history of seeing a cancer specialist in the last 2 years (PR = 2.58; 95% CI, 1.53-4.33), or having a colonoscopy (PR = 2.02; 95% CI, 1.17-3.48) or echocardiogram (PR = 6.42; 95% CI, 1.54-26.85) were more likely to have had a carotid ultrasound.Many survivors do not undergo carotid ultrasound despite meeting existing guidelines. Health care delivery features such as having seen a cancer specialist or having other testing are relevant.© 2024 American Cancer Society.