目的是使用成像（超声、对比增强计算机断层扫描 (CT) 和全身扩散加权磁共振成像 (WB-DWI/MRI)）评估腹膜癌指数 (PCI) 在评估腹膜癌病方面的表现并预测输卵管卵巢癌患者的不可切除性。这是一项前瞻性多中心观察性研究，考虑了所有术前接受超声、CT 和 WB-DWI/MRI（如果有）的疑似原发性卵巢/输卵管/腹膜癌患者。评估方法在预测不可切除性方面的性能的最佳截止值是在敏感性和特异性最相似的点确定的，预测不可切除性的参考标准是残余病灶的手术结果>。 1 cm 或手术不可行。使用组内相关系数 (ICC) 评估 PCI 评分中包含的评估部位的成像方法和手术探查之间的一致性。从 2020 年 1 月到 2022 年 11 月，纳入了 242 名患者。最佳 PCI 截止值预测手术探查不可切除性的指标为 >12，其最佳 AUC 为 0.87，其次是超声，截止值 >10，AUC 为 0.81，WB-DWI/MRI，截止值 >12， AUC 为 0.81，CT 截止值 >11，AUC 为 0.74。使用 ICC，超声与外科 PCI 具有非常高的一致性 (0.94)，而 CT 和 WB-DWI/MRI 具有很高的一致性（分别为 0.86 和 0.87）。与 WB 相比，由专家操作员执行的超声与手术结果具有最佳一致性-DWI/MRI 和 CT 评估放射学 PCI。在预测不可切除性方面，超声不劣于 CT，但未证明其不劣于 WB-DWI/MRI。版权所有 © 2024。由 Elsevier Inc. 出版。

The aim was to evaluate the performance of the Peritoneal Cancer Index (PCI) using imaging (ultrasound, contrast-enhanced computed tomography (CT), and whole-body diffusion-weighted magnetic resonance imaging (WB-DWI/MRI) in assessing peritoneal carcinomatosis and predicting non-resectability in tubo-ovarian carcinoma patients.This was a prospective multicenter observational study. We considered all patients with suspected primary ovarian/tubal/peritoneal cancer who underwent preoperative ultrasound, CT, and WB-DWI/MRI (if available). The optimal cut off value for assessing the performance of the methods in predicting non-resectability was identified at the point at which the sensitivity and specificity were most similar. The reference standard to predict non-resectability was surgical outcome in terms of residual disease >1 cm or surgery not feasible. Agreement between imaging methods and surgical exploration in assessing sites included in the PCI score was evaluated using the Intraclass Correlation Coefficient (ICC).242 patients were included from January 2020 until November 2022. The optimal PCI cut-off for predicting non-resectability for surgical exploration was >12, which achieved the best AUC of 0.87, followed by ultrasound with a cut-off of >10 and AUC of 0.81, WB-DWI/MRI with a cut-off of >12 and AUC of 0.81, and CT with a cut-off of >11 and AUC of 0.74. Using ICC, ultrasound had very high agreement (0.94) with surgical PCI, while CT and WB-DWI/MRI had high agreement (0.86 and 0.87, respectively).Ultrasound performed by an expert operator had the best agreement with surgical findings compared to WB-DWI/MRI and CT in assessing radiological PCI. In predicting non-resectability, ultrasound was non-inferior to CT, while its non-inferiority to WB-DWI/MRI was not demonstrated.Copyright © 2024. Published by Elsevier Inc.