研究动态
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小儿眼睑皮角:病例系列和文献综述。

Pediatric Eyelid Cutaneous Horns: A Case Series and Literature Review.

发表日期:2024 Oct 09
作者: Ramez Barbara, Ahmed M Abdelaal, Rebecca Levy, Anita Nagy, Kamiar Mireskandari, Asim Ali
来源: AMERICAN JOURNAL OF OPHTHALMOLOGY

摘要:

描述小儿眼睑皮角的临床和组织病理学特征。回顾性观察病例系列和文献复习。5例眼睑皮角小儿患者方法:利用科室数据库回顾性鉴定5例眼睑皮角病例。对患者记录的人口统计数据、临床表现、组织学结果和临床病程进行分析。对 3 名患者进行了病变切除活检。其余 2 例患者采用保守治疗。临床结果和组织病理学评估重点是排除恶性肿瘤。所有 5 例皮角病变均通过手术或保守治疗得到缓解。就诊时的平均年龄为 6.6 岁(范围 5-11 岁)。临床上,4 个病变之前有麦粒肿或霰粒肿,所有切除的病变在组织学检查中均具有良性特征。未观察到有丝分裂或异型性。在1至96个月的随访期间,所有患者均未出现复发。通过查阅文献,发现了 5 例之前的 5 份报告。我们的病例系列将这个数字加倍,以支持儿童这些病变的良性性质。小儿眼睑皮角与眼睑边缘炎症性疾病密切相关,并且似乎遵循良性病程。这与成年人群形成鲜明对比,在成年人群中,皮角经常与肿瘤相关。版权所有 © 2024。由 Elsevier Inc. 出版。
To describe the clinical and histopathologic features of pediatric eyelid cutaneous horns.Retrospective observational case series and review of literature.Five pediatric patients with eyelid cutaneous horns Methods: Five cases with eyelid cutaneous horns were retrospectively identified using departmental databases. Patients' records were analyzed for demographic data, clinical appearance, histologic findings, and clinical course. An excisional biopsy of the lesion was performed in 3 patients. The remaining 2 patients were managed conservatively.Clinical outcome and histopathologic evaluation with emphasis on excluding malignancy.All 5 cutaneous horn lesions resolved surgically or conservatively. The average age at presentation was 6.6 years (range 5-11 years). Clinically, 4 lesions were preceded by a hordeolum or chalazion and all excised lesions had benign features on histologic examination. Mitotic figures or atypia were not observed. None of the patients developed recurrence during the follow-up period ranging from 1 to 96 months. Five previous reports of five cases were found on review of the literature. Our case series doubles this number to support the benign nature of these lesions in children.Pediatric eyelid cutaneous horns are closely related to eyelid margin inflammatory disease and appear to follow a benign course. This contrasts with the adult population where cutaneous horns are frequently associated with neoplasia.Copyright © 2024. Published by Elsevier Inc.