当高能重离子与任何目标相互作用时，会产生短程、高线性能量转移 (LET) 目标碎片。在重离子癌症治疗期间以及宇宙辐射与宇航员相互作用时，这些目标碎片 (TF) 可以给健康组织带来显着的剂量。本文介绍了蒙特卡罗模拟，使用粒子和重离子传输代码系统 (PHITS) 来表征氦和碳离子与水反应的目标碎片。给出了计算的范围、LET、剂量和生产截面。结果表明，当碳和氦离子与水碰撞时，质子、氘核、氚核、α粒子、3He、6He、氮、氧和氟离子是最可能的目标碎片。在产生的靶片段中，α粒子和氮离子给予靶的剂量最高，因为这些TF的注量和LET的组合在产生的片段中最高。当氦和碳离子撞击水时，质子和氧的产生截面是目标碎片截面中最高的，因为与其他碎片相比，这些TF可以通过更多的反应通道产生。这些发现有助于重离子癌症治疗期间准确的剂量测量和空间辐射的屏蔽。版权所有 © 2024 作者。由 Elsevier GmbH 出版。保留所有权利。

When high energetic heavy ions interact with any target, short range, high linear energy transfer (LET) target fragments are produced. These target fragments (TFs) can give a significant dose to the healthy tissue during heavy ion cancer therapy, and when cosmic radiation interacts with astronauts. This paper presents Monte Carlo simulations, using the Particle and Heavy Ion Transport code System (PHITS), to characterize target fragments from reactions of helium and carbon ions with water. The calculated ranges, LET, doses, and production cross sections are presented. It is shown that protons, deuterons, tritons, alpha particles, 3He, 6He, nitrogen, oxygen, and fluorine ions are the most probable target fragments when carbon and helium ions collide with water. Among the produced target fragments, alpha particles and nitrogen ions give the highest dose to the targets, since the combination of fluence and LETs of these TFs are highest among the produced fragments. The production cross sections of proton and oxygen are the highest among the target fragments cross sections when helium and carbon ions imping on water, because these TFs can be produced through more reaction channels compared to other fragments. These findings are helpful for accurate dose measurement during heavy ion cancer therapy and for shielding of space radiation.Copyright © 2024 The Author(s). Published by Elsevier GmbH.. All rights reserved.