氦核和碳离子与水反应产生靶碎片的蒙特卡洛模拟计算
Monte Carlo calculations of target fragments from helium and carbon ion interactions with water
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影响因子:4.2
分区:医学4区 / 核医学4区
发表日期:2024 Oct 10
作者:
Quazi Muhammad Rashed Nizam, Asif Ahmed, Iftekhar Ahmed, Lembit Sihver
DOI:
10.1016/j.zemedi.2024.09.003
摘要
高能重离子与任何靶材相互作用时，会产生短程、高线性能量转移（LET）的靶碎片（TFs）。这些靶碎片在重离子放疗癌症治疗和宇宙辐射作用时，可能对健康组织造成显著剂量。本文利用粒子与重离子输运码系统（PHITS）进行了蒙特卡洛模拟，旨在表征氦核和碳离子与水反应产生的靶碎片。给出了计算的穿透距离、LET、剂量和产率截面数据。结果显示，质子、氘核、中子、α粒子、3He、6He、氮、氧和氟离子是碳和氦离子与水碰撞时最可能产生的靶碎片。在所有靶碎片中，α粒子和氮离子对目标的剂量贡献最大，因为它们的通量与LET值之积最高。氢和氧的产率截面在靶碎片中也最高，因为它们可以通过更多反应通道产生。这些研究结果有助于在重离子癌症治疗中实现精确剂量测量及空间辐射的屏蔽设计。
Abstract
When high energetic heavy ions interact with any target, short range, high linear energy transfer (LET) target fragments are produced. These target fragments (TFs) can give a significant dose to the healthy tissue during heavy ion cancer therapy, and when cosmic radiation interacts with astronauts. This paper presents Monte Carlo simulations, using the Particle and Heavy Ion Transport code System (PHITS), to characterize target fragments from reactions of helium and carbon ions with water. The calculated ranges, LET, doses, and production cross sections are presented. It is shown that protons, deuterons, tritons, alpha particles, 3He, 6He, nitrogen, oxygen, and fluorine ions are the most probable target fragments when carbon and helium ions collide with water. Among the produced target fragments, alpha particles and nitrogen ions give the highest dose to the targets, since the combination of fluence and LETs of these TFs are highest among the produced fragments. The production cross sections of proton and oxygen are the highest among the target fragments cross sections when helium and carbon ions imping on water, because these TFs can be produced through more reaction channels compared to other fragments. These findings are helpful for accurate dose measurement during heavy ion cancer therapy and for shielding of space radiation.