美国各州年轻女性与男性肺癌发病率对比
Lung cancer incidence rates in young women and men by state in the United States
DOI 原文链接
用sci-hub下载
如无法下载，请从 Sci-Hub 选择可用站点尝试。
影响因子:4.7
分区:医学2区 / 肿瘤学2区
发表日期:2025 Feb 01
作者:
Ahmedin Jemal, Elizabeth J Schafer, Jessica Star, Priti Bandi, Hyuna Sung, Farhad Islami, Rebecca L Siegel
DOI:
10.1002/ijc.35188
摘要
此前研究报道，在美国35-54岁人群中，女性肺癌发病率高于男性，逆转了历史上男性发病率较高的趋势。我们考察这种模式是否随州而异。基于癌症在北美数据库中2015-2019年间35-54岁成年人肺癌发病率数据，以及行为风险因素监测系统（BRFSS）中2004-2005年20-39岁成年人吸烟流行率的历史数据，发现女性的发病率在51个州中有40个州等于或高于男性，且在20个州差异具有统计学意义（双侧p<.05）。相较之下，女性的当前吸烟和既往吸烟流行率在统计学上明显低于（33和34个州）或与男性相近。此外，历史吸烟流行率的差异与性别肺癌发病率之间没有相关性。在大多数州，年轻女性的肺癌发病率高于年轻男性，这一差异不能用吸烟流行率的差异来解释。
Abstract
Previous studies reported higher lung cancer incidence in women than men among persons aged 35-54 years in the United States, a reversal of historically higher rates in men. We examined whether this pattern varies by state. Based on lung cancer incidence (2015-2019) data among adults aged 35-54 years from Cancer in North America database and historical cigarette smoking prevalence data (2004-2005) among adults 20-39 years from the Behavioral Risk Factor Surveillance System, incidence rates in women were equal to or higher than rates in their male counterparts in 40 of 51 states, with statistically significant differences in 20 states (two-sided, p < .05). In contrast, current and ever smoking prevalence in women compared to men was statistically significantly lower (33 and 34 states, respectively) or similar. Furthermore, there was no association between differences in historical smoking prevalence and lung cancer incidence by sex. Lung cancer incidence rate is higher in young women than young men in most states and is unexplained by differences in smoking prevalence.