医院衰弱风险评分 (HFRS) 等自动衰弱筛查工具主要针对护理消费结果进行验证。我们使用 Geriatric 8 (G8) 筛查工具作为临床基准，评估了 HFRS 对患有癌症的老年人的护理消费结果、虚弱域损伤和死亡率的预测能力。这项回顾性、基于关联的研究包括年龄≥70 岁的患者患有实体瘤多年，参加了老年癌症患者 (ELCAPA) 多中心队列研究（2016-2020），并在大巴黎大学医院住院接受急性护理。 HFRS 评分包括医院获得性问题和虚弱相关综合征，是使用指数入院和前 6 个月的数据计算的。在 ELCAPA 纳入中进行了多领域老年评估 (GA)，包括认知、营养、情绪、功能状态、行动能力、合并症、多药治疗、失禁和社会环境，并计算了 G8 评分。 Logistic 和 Cox 回归测量了 G8、HFRS、GA 域改变、住院时间超过 10 天、30 天再入院和死亡率之间的关联。在 587 名患者中（中位年龄 82 岁，转移性癌症 47.0%），237 名（40.4 %) 因 HFRS (HFRS>5) 增加了虚弱风险，261 (47.5%) 因 G8 (G8≤10) 增加了虚弱风险。 HFRS 和 G8 均与认知和功能障碍、失禁、合并症、住院时间延长和 30 天死亡率显着相关。 G8 与复方用药、营养和情绪障碍相关。尽管与短期护理消费显着相关，但 HFRS 无法识别复方用药、营养、情绪和社会环境障碍，并且在所有 GA 领域中表现出较低的辨别能力。© 作者(s) 2024。由牛津大学出版社代表英国老年医学会出版。版权所有。如需权限，请发送电子邮件至：journals.permissions@oup.com。

Automated frailty screening tools like the Hospital Frailty Risk Score (HFRS) are primarily validated for care consumption outcomes. We assessed the predictive ability of the HFRS regarding care consumption outcomes, frailty domain impairments and mortality among older adults with cancer, using the Geriatric 8 (G8) screening tool as a clinical benchmark.This retrospective, linkage-based study included patients aged ≥70 years with solid tumor, enrolled in the Elderly Cancer Patients (ELCAPA) multicentre cohort study (2016-2020) and hospitalized in acute care within the Greater Paris University Hospitals. HFRS scores, which encompass hospital-acquired problems and frailty-related syndromes, were calculated using data from the index admission and the preceding 6 months. A multidomain geriatric assessment (GA), including cognition, nutrition, mood, functional status, mobility, comorbidities, polypharmacy, incontinence, and social environment, was conducted at ELCAPA inclusion, with computation of the G8 score. Logistic and Cox regressions measured associations between the G8, HFRS, altered GA domains, length of stay exceeding 10 days, 30-day readmission, and mortality.Among 587 patients included (median age 82 years, metastatic cancer 47.0%), 237 (40.4%) were at increased frailty risk by the HFRS (HFRS>5) and 261 (47.5%) by the G8 (G8≤10). Both HFRS and G8 were significantly associated with cognitive and functional impairments, incontinence, comorbidities, prolonged length of stay, and 30-day mortality. The G8 was associated with polypharmacy, nutritional and mood impairment.Although showing significant associations with short-term care consumption, the HFRS could not identify polypharmacy, nutritional, mood and social environment impairments and showed low discriminatory ability across all GA domains.© The Author(s) 2024. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.