靶向生长抑素受体的 68Ga-DOTATATE PET/CT 通常用于神经内分泌肿瘤的成像。然而，其他恶性肿瘤，如淋巴瘤（霍奇金和非霍奇金）也有生长抑素受体的表达，尽管与神经内分泌肿瘤相比程度较低，因此 68Ga-DOTATATE PET/CT 可能呈阳性。我们描述了一种模仿转移性神经内分泌肿瘤的侵袭性大 B 细胞淋巴瘤的非典型表现，在 68Ga-DOTATATE PET/CT 上显示出高生长抑素受体表达，随后在 18F-FDG PET/CT 上显示出快速进展的病程。版权所有 © 2024 Wolters Kluwer Health, Inc. 保留所有权利。

68Ga-DOTATATE PET/CT targeting somatostatin receptors is commonly utilized in the imaging of neuroendocrine tumors. However, other malignancies such as lymphomas (both Hodgkin and non-Hodgkin) also have expression of somatostatin receptors, albeit to a lesser degree compared with the neuroendocrine tumors, and thus can be positive on a 68Ga-DOTATATE PET/CT. We describe an atypical presentation of an aggressive large B-cell lymphoma mimicking a metastatic neuroendocrine tumor at initial presentation with high somatostatin receptor expression demonstrated on the 68Ga-DOTATATE PET/CT and a rapidly progressing course on the subsequent 18F-FDG PET/CT.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.