慢性胆囊炎急性加重患者的 18F-FDG 阴性和 68Ga-FAPI-04 阳性结果。
Negative 18F-FDG and Positive 68Ga-FAPI-04 Findings in a Patient With Acute Exacerbation of Chronic Cholecystitis.
发表日期：2024 Oct 14
作者：
Na Qi, Jie Ding, Haiyan Wang, Jun Zhao
来源：
CLINICAL NUCLEAR MEDICINE
摘要：
急性胆囊炎通常表现为胆囊壁强烈摄取 FDG。放射性标记的成纤维细胞活化蛋白抑制剂（FAPI）被认为是肿瘤特异性成像的潜在替代药物。我们报告了一名 44 岁慢性胆囊炎急性加重女性的 18F-FDG 和 68Ga-FAPI-04 PET/MR 结果。 PET/MR 中病变显示 18F-FDG 摄取呈阴性，但 68Ga-FAPI-04 摄取强烈。该病例强调了核医学临床医生在评估表现出强烈 68Ga-FAPI-04 但阴性 18F-FDG 摄取的胆囊病变时必须保持警惕。版权所有 © 2024 Wolters Kluwer Health, Inc. 保留所有权利。
Acute cholecystitis typically exhibits intense FDG uptake of the gallbladder wall. Radiolabeled fibroblast activation protein inhibitor (FAPI) is considered as a potential alternative agent for tumor-specific imaging. We report 18F-FDG and 68Ga-FAPI-04 PET/MR findings in a 44-year-old woman with acute exacerbation of chronic cholecystitis. The lesions show negative 18F-FDG uptake but intense 68Ga-FAPI-04 uptake in PET/MR. This case highlights the imperative for nuclear medicine clinicians to exercise vigilance when evaluating gallbladder lesions exhibiting intense 68Ga-FAPI-04 but negative 18F-FDG uptake.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.