如今，癌症仍然对人类健康构成重大威胁。尽管饥饿疗法和其他治疗方法最近在肿瘤治疗方面已发展到快速发展的新水平，但其有限的治疗效果和意想不到的副作用使它们无法成为临床治疗的首选。随着纳米技术的快速发展，纳米材料在治疗中的应用为解决癌症治疗的缺点提供了潜力。值得注意的是，多功能金属有机框架（MOF）由于其形状可定制、直径可调、孔隙率高、成分多样、比表面积大、功能化程度高、生物相容性强等优点，在癌症治疗中得到了广泛的应用。本文综述了基于MOF的多功能纳米平台用于癌症饥饿治疗的当前进展和成功，以及MOF纳米平台在癌症饥饿治疗中应用的前景和潜在障碍。

Cancer remains a significant threat to human health today. Even though starvation therapy and other treatment methods have recently advanced to a new level of rapid development in tumour treatment, their limited therapeutic effectiveness and unexpected side effects prevent them from becoming the first option in clinical treatment. With rapid advancement in nanotechnology, the utilization of nanomaterials in therapeutics offers the potential to address the shortcomings in cancer treatment. Notably, multifunctional metal-organic framework (MOF) has been widely employed in cancer therapy due to their customizable shape, adjustable diameter, high porosity, diverse compositions, large specific surface area, high degree of functionalization and strong biocompatibility. This paper reviews the current progress and success of MOF-based multifunctional nanoplatforms for cancer starvation therapy, as well as the prospects and potential barriers for the application of MOF nanoplatforms in cancer starvation therapy.