采用定性和定量的方法分析肾实体瘤高帧率超声造影（H-CEUS）的特点。 75例术前接受常规超声（US）、常规超声造影（C-对肾肿瘤的CEUS)、H-CEUS检查进行回顾性分析，共89个肾肿瘤。根据增强计算机断层扫描和病理结果将肿块分为良性组（30个肿块）和恶性组（59个肿块）。超声观察病灶的位置、直径、形状、边界、钙化和彩色多普勒血流成像（CDFI），并对C-CEUS和H-CEUS图像特征进行定性和定量分析。采用χ2检验或Fisher精确概率法比较良恶性组之间的US图像特征以及良恶性组之间C-CEUS和H-CEUS的图像特征。此外，采用非参数Mann-Whitney检验比较C-CEUS和H-CEUS时间强度曲线（TIC）参数的差异。恶性与良性肿瘤在性别、手术入路、回声及CDFI等方面均存在显着差异。组（p = 0.003，< 0.001，< 0.001，= 0003）。定性分析还显示，恶性组中 C-CEUS 和 H-CEUS 的清除模式和填充方向存在显着差异（p = 0.041、0.002）。此外，良性组中两种对比模型之间的增强均匀性显示出显着差异（p = 0.009）。定量分析表明，与 C-CEUS 模型相比，H-CEUS 模型中的 TIC 参数峰值强度 (PI)、减速时间 (DT) /2、曲线下面积 (AUC) 和平均转变时间 (MTT) 显着降低。良性和恶性组的CEUS模型。 （所有 p < 0.001）。相比之下，恶性组中H-CEUS模型的上升曲线上升斜率（AS）显着高于C-CEUS模型（p = 0.048）。在肾肿瘤中，H-CEUS显示出更清晰的内部强化质量和洗脱期的变化。与 C-CEUS 相比，H-CEUS 的定量 TIC 参数 PI、DT/2、AUC 和 MTT 较低。定量和定性分析均表明，与 C-CEUS 相比，H-CEUS 更好地显示了肾脏实性肿块的特征。© 2024。作者。

To analyze the characteristics of high-frame-rate contrast-enhanced ultrasound (H-CEUS) in solid renal tumors using qualitative and quantitative methods.Seventy-five patients who underwent preoperative conventional ultrasound (US), conventional contrast-enhanced ultrasound (C-CEUS), and H-CEUS examination of renal tumors were retrospectively analyzed, with a total of 89 renal masses. The masses were divided into the benign (30 masses) and malignant groups (59 masses) based on the results of enhanced computer tomography and pathology. The location, diameter, shape, border, calcification, and color doppler blood flow imaging (CDFI) of the lesions were observed by US, and the characteristics of the C-CEUS and H-CEUS images were qualitatively and quantitatively analyzed. The χ² test or Fisher's exact probability method was used to compare the US image characteristics between the benign and malignant groups, and the image characteristics of C-CEUS and H-CEUS between the benign and malignant groups. Moreover, the nonparametric Mann-Whitney test was used to compare the differences in C-CEUS and H-CEUS time-intensity curve (TIC) parameters.Significant differences in gender, surgical approach, echogenicity, and CDFI were observed between the malignant and benign groups (p = 0.003, < 0.001, < 0.001, = 0003). Qualitative analysis also revealed significant differences in the mode of wash-out and fill-in direction between C-CEUS and H-CEUS in the malignant group (p = 0.041, 0.002). In addition, the homogeneity of enhancement showed significant differences between the two contrast models in the benign group (p = 0.009). Quantitative analysis indicated that the TIC parameters peak intensity (PI), deceleration time (DT) /2, area under the curve (AUC), and mean transition time (MTT) were significantly lower in the H-CEUS model compared to the C-CEUS model in both the benign and malignant groups. (all p < 0.001). In contrast, ascending slope of rise curve (AS) was significantly higher in the H-CEUS model compared to the C-CEUS model in the malignant group (p = 0.048).In renal tumors, H-CEUS shows clearer internal enhancement of the mass and the changes in the wash-out period. The quantitative TIC parameters PI, DT/2, AUC, and MTT were lower in H-CEUS compared to C-CEUS. Both the quantitative and qualitative analyses indicated that H-CEUS better displays the characteristics of solid renal masses compared with C-CEUS.© 2024. The Author(s).