通过高框架对比度增强超声对固体肾肿瘤进行定性和定量分析

使用定性和定量方法分析固体肾脏肿瘤中高率率对比度增强的超声（H-CEU）的特征。七十五名接受了术前常规超声（US）的患者，常规对比度增强超声超声超声（C-CEUS）的特征，以及肾脏的总体概念性分析，以及89个肾脏分析。根据增强的计算机断层扫描和病理学的结果，将质量分为良性（30个质量）和恶性群（59个质量）。我们观察到了病变的位置，直径，形状，边界，钙化和颜色多普勒血液流量成像（CDFI），并且在定性和定量上分析了C-CEUS和H-CEUS图像的特征。 χ²检验或Fisher的确切概率方法用于比较良性和恶性基团之间的美国图像特征，以及良性和恶性组之间C-CEUS和H-CEUS的图像特征。此外，使用非参数Mann-Whitney检验来比较C-CEUS和H-CEUS时间强度曲线（TIC）参数的差异。在恶性和良性组之间观察到性别，手术方法，回声方法和CDFI的性别差异（p = 0.003，p = 0.003，<0.003，<0.001，<0.001，<0.001，<0.001，<0.001，<0.001，<00001,0001，= 00001，=0000。定性分析还显示，在恶性组中，C-CEUS和H-CEUS之间的冲洗和填充方向的填充方向存在显着差异（P = 0.041，0.002）。此外，增强的均匀性显示了良性组的两个对比模型之间的显着差异（p = 0.009）。定量分析表明，在H-CEUS模型中，TIC参数峰值强度（PI），曲线（AUC）下的面积（AUC）和平均过渡时间（MTT）在良性和恶性组中的C-CEUS模型中的平均值（MTT）显着较低。 （全p <0.001）。相反，与恶性组的C-CEUS模型相比，H-CEUS模型中上升曲线的上升斜率明显更高（p = 0.048）。在肾脏肿瘤中，H CEUS显示质量的内部增强和洗涤期的变化更清晰。与C-CEUS相比，H-CEUS中的定量TIC参数PI，DT/2，AUC和MTT较低。定量和定性分析都表明，与C-CEUS相比，H-CEUS更好地显示出固体肾脏的特征。

To analyze the characteristics of high-frame-rate contrast-enhanced ultrasound (H-CEUS) in solid renal tumors using qualitative and quantitative methods.Seventy-five patients who underwent preoperative conventional ultrasound (US), conventional contrast-enhanced ultrasound (C-CEUS), and H-CEUS examination of renal tumors were retrospectively analyzed, with a total of 89 renal masses. The masses were divided into the benign (30 masses) and malignant groups (59 masses) based on the results of enhanced computer tomography and pathology. The location, diameter, shape, border, calcification, and color doppler blood flow imaging (CDFI) of the lesions were observed by US, and the characteristics of the C-CEUS and H-CEUS images were qualitatively and quantitatively analyzed. The χ² test or Fisher's exact probability method was used to compare the US image characteristics between the benign and malignant groups, and the image characteristics of C-CEUS and H-CEUS between the benign and malignant groups. Moreover, the nonparametric Mann-Whitney test was used to compare the differences in C-CEUS and H-CEUS time-intensity curve (TIC) parameters.Significant differences in gender, surgical approach, echogenicity, and CDFI were observed between the malignant and benign groups (p = 0.003, < 0.001, < 0.001, = 0003). Qualitative analysis also revealed significant differences in the mode of wash-out and fill-in direction between C-CEUS and H-CEUS in the malignant group (p = 0.041, 0.002). In addition, the homogeneity of enhancement showed significant differences between the two contrast models in the benign group (p = 0.009). Quantitative analysis indicated that the TIC parameters peak intensity (PI), deceleration time (DT) /2, area under the curve (AUC), and mean transition time (MTT) were significantly lower in the H-CEUS model compared to the C-CEUS model in both the benign and malignant groups. (all p < 0.001). In contrast, ascending slope of rise curve (AS) was significantly higher in the H-CEUS model compared to the C-CEUS model in the malignant group (p = 0.048).In renal tumors, H-CEUS shows clearer internal enhancement of the mass and the changes in the wash-out period. The quantitative TIC parameters PI, DT/2, AUC, and MTT were lower in H-CEUS compared to C-CEUS. Both the quantitative and qualitative analyses indicated that H-CEUS better displays the characteristics of solid renal masses compared with C-CEUS.