诊断常见的良性皮肤肿瘤。
Diagnosing Common Benign Skin Tumors.
发表日期:2024 Oct
作者:
Joy Shen-Wagner, Joel Amidon, Stephen Carek
来源:
AMERICAN FAMILY PHYSICIAN
摘要:
患者通常会向家庭医生提出皮肤检查结果,区分常见的良性皮肤肿瘤和潜在的恶性肿瘤非常重要。良性皮肤肿瘤通常可以通过其病史、分布和特征形态来诊断。如果诊断不确定或病变发生不典型或快速变化,则需要进行活检或切除。角化棘皮瘤是一种具有中央凹陷的圆顶形结节,即使通过皮肤镜检查也很难与鳞状细胞癌区分开。毛发囊肿通常是良性的,但快速生长的类型可能具有恶性性质。如果不治疗,皮样囊肿可能会扩展到颅内,具体取决于其位置。尽管皮肤纤维瘤和脂溢性角化病是良性的,但非典型表现必须与黑色素瘤鉴别。皮脂腺增生可模仿早期基底细胞癌。樱桃状血管瘤、腋索瘤、生长缓慢的毛发囊肿和皮肤纤维瘤的治疗选择应根据皮肤类型、病变特征和患者的美容偏好进行个体化。一般来说,切除是角化棘皮瘤、快速增殖的毛囊囊肿和皮样囊肿的首选治疗方法。樱桃状血管瘤可采用激光治疗,皮脂腺增生可采用电干燥治疗。肩胛骨和脂溢性角化病的常见治疗方法是剃毛切除和冷冻疗法。化脓性肉芽肿有时会自行消退,但容易出血,且常在原位复发。他们通常对剃须、切除和电干燥有反应。对于肤色较深的患者,冷冻疗法和激光疗法应包括有关色素沉着不足风险的讨论。
Patients commonly present to family physicians with skin findings, and distinguishing common benign skin tumors from potentially malignant tumors is important. Benign skin tumors can often be diagnosed by their history, distribution, and characteristic morphology. A biopsy or excision is indicated if there is diagnostic uncertainty or the lesion undergoes uncharacteristic or rapid change. A keratoacanthoma is a dome-shaped nodule with a central crater and can be difficult to distinguish from squamous cell carcinomas even with dermoscopy. Pilar cysts are typically benign, but rapidly growing types could have malignant qualities. Dermoid cysts, depending on their location, can have intracranial extension if untreated. Although dermatofibromas and seborrheic keratoses are benign, atypical presentations must be differentiated from melanomas. Sebaceous hyperplasia can mimic early basal cell carcinoma. Treatment options for cherry angiomas, acrochordons, slow-growing pilar cysts, and dermatofibromas should be individualized to skin type, lesion characteristics, and the patient's cosmetic preference. Generally, excision is the treatment of choice for keratoacanthomas, rapidly proliferating pilar cysts, and dermoid cysts. Cherry angiomas are treated with laser therapy and sebaceous hyperplasia with electrodesiccation. Common treatments for acrochordons and seborrheic keratoses are shave excision and cryotherapy. Pyogenic granulomas sometimes self-involute but bleed easily and often recur at the original site. They generally respond to shave excision and electrodesiccation. In patients with darker skin, treatment with cryotherapy and laser therapy should include discussions about hypopigmentation risk.