特发性肉芽肿性乳腺炎（IGM）由于其多样化的临床和放射学表现（通常类似于恶性肿瘤）而给诊断带来了挑战。本研究旨在评估动态对比增强 MRI (DCE-MRI) 中多模态超声对 IGM 和乳腺癌肿块和非肿块增强的诊断效果。一项回顾性分析涉及经组织病理学证实患有 IGM 和 BC 的患者。所有患者均接受常规超声（C-US）、超声弹性成像（UE）、超声造影（CEUS）和DCE-MRI检查。经验丰富的放射科医生对影像学结果进行盲法评估。计算了肿块和非肿块增强的诊断准确性、敏感性和特异性。对于肿块增强 (ME)，多模态超声表现出强大的功效（AUC = 0.8651，95% CI：0.7431 至 0.9871），表现出高灵敏度 (83.3%)以及区分 IGM 和乳腺癌的特异性 (92.4%)。然而，对于非肿块增强 (NME)，多模态超声在区分 IGM 和乳腺癌方面的准确性有限 (AUC = 0.6306)，敏感性 (65.6%) 和特异性 (81.2%) 较低。多模态超声对肿块表现出良好的诊断功效DCE-MRI 对 IGM 和乳腺癌的增强，而对于非肿块增强模式，DCE-MRI 仍然是全面评估这种情况复杂性的最有价值的放射学方式。版权所有 © 2024 作者。由爱思唯尔有限公司出版。保留所有权利。

Idiopathic granulomatous mastitis (IGM) poses diagnostic challenges due to its diverse clinical and radiological presentations, often mimicking malignancies. This study aimed to assess the diagnostic efficacy of multimodal ultrasound for mass and non-mass enhancements in Dynamic Contrast-Enhanced MRI (DCE-MRI) of IGM and breast cancer.A retrospective analysis involved patients confirmed histopathologically with IGM and BC. All patients underwent conventional ultrasound (C-US), ultrasound elastography (UE), contrast-enhanced ultrasound (CEUS), and DCE-MRI examinations. Blinded experienced radiologists assessed imaging findings. Diagnostic accuracy, sensitivity, and specificity were calculated for mass and non-mass enhancements.For mass enhancements (ME), multimodal ultrasound demonstrated strong efficacy (AUC = 0.8651, 95 % CI: 0.7431 to 0.9871), exhibiting high sensitivity (83.3 %) and specificity (92.4 %) in differentiating IGM from breast cancer. However, for non-mass enhancements (NME), multimodal ultrasound showed limited accuracy (AUC = 0.6306) with lower sensitivity (65.6 %) and specificity (81.2 %) in distinguishing between IGM and breast cancer.Multimodal ultrasound displayed good diagnostic efficacy for mass enhancements in DCE-MRI for IGM and breast cancer, while for non-mass enhancement patterns, DCE-MRI remains the most valuable radiological modality for comprehensively assessing this condition's complexities.Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.