MRI对质量和非质量增强的多模式超声评估：特发性肉芽肿性乳腺炎和乳腺癌的诊断准确性
Multimodal ultrasound assessment of mass and non-mass enhancements by MRI: Diagnostic accuracy in idiopathic granulomatous mastitis and breast cancer
影响因子:7.90000
分区:医学2区 / 妇产科学2区 肿瘤学2区
发表日期:2024 Dec
作者:
Liang Yin, Xi Wei, Qing Zhang, Lingling Xiang, Yun Zhang, Deqian Wang, Peiqin Chen, Xuan Cao, Zakari Shaibu, Rong Qin
摘要
特发性肉芽肿性乳腺炎（IGM）由于其多样化的临床和放射学表现而提出诊断挑战，通常会模仿恶性肿瘤。这项研究旨在评估多模式超声对IGM和乳腺癌的动态对比增强MRI（DCE-MRI）中质量和非质量增强的诊断功效。一种回顾性分析涉及患者在IGM和BC中证实了组织病理学的患者。所有患者均接受了常规超声（C-US），超声弹性图（UE），对比增强超声（CEU）和DCE-MRI检查。盲人经验丰富的放射科医生评估了成像发现。计算质量和非质量增强的诊断准确性，敏感性和特异性。对于质量增强（ME），多模式超声检查表现出很强的功效（AUC = 0.8651，95％CI：0.7431：0.7431至0.9871），表现出高度敏感性（83.3％）和特异性（92.4％）在不同的（92.4％）中表现出高度的效果。 However, for non-mass enhancements (NME), multimodal ultrasound showed limited accuracy (AUC = 0.6306) with lower sensitivity (65.6 %) and specificity (81.2 %) in distinguishing between IGM and breast cancer.Multimodal ultrasound displayed good diagnostic efficacy for mass enhancements in DCE-MRI for IGM and breast cancer, while for non-mass enhancement patterns, DCE-MRI仍然是最有价值的放射学方式，用于全面评估该情况的复杂性。
Abstract
Idiopathic granulomatous mastitis (IGM) poses diagnostic challenges due to its diverse clinical and radiological presentations, often mimicking malignancies. This study aimed to assess the diagnostic efficacy of multimodal ultrasound for mass and non-mass enhancements in Dynamic Contrast-Enhanced MRI (DCE-MRI) of IGM and breast cancer.A retrospective analysis involved patients confirmed histopathologically with IGM and BC. All patients underwent conventional ultrasound (C-US), ultrasound elastography (UE), contrast-enhanced ultrasound (CEUS), and DCE-MRI examinations. Blinded experienced radiologists assessed imaging findings. Diagnostic accuracy, sensitivity, and specificity were calculated for mass and non-mass enhancements.For mass enhancements (ME), multimodal ultrasound demonstrated strong efficacy (AUC = 0.8651, 95 % CI: 0.7431 to 0.9871), exhibiting high sensitivity (83.3 %) and specificity (92.4 %) in differentiating IGM from breast cancer. However, for non-mass enhancements (NME), multimodal ultrasound showed limited accuracy (AUC = 0.6306) with lower sensitivity (65.6 %) and specificity (81.2 %) in distinguishing between IGM and breast cancer.Multimodal ultrasound displayed good diagnostic efficacy for mass enhancements in DCE-MRI for IGM and breast cancer, while for non-mass enhancement patterns, DCE-MRI remains the most valuable radiological modality for comprehensively assessing this condition's complexities.