研究动态
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心脏肿瘤学和心力衰竭:美国心力衰竭协会的科学声明。

Cardio-Oncology and Heart Failure: A Scientific Statement from the Heart Failure Society of America.

发表日期:2024 Sep 18
作者: Michelle Weisfelner Bloom, Jacqueline B Vo, Jo Ellen Rogers, Alana Ferrari, Anju Nohria, Anita Deswal, Richard K Cheng, Michelle M Kittleson, Jenica N Upshaw, Nicholas Palaskas, Anne Blaes, Sherry-Ann Brown, Bonnie Ky, Daniel Lenihan, Mathew S Maurer, Anecita Fadol, Kerry Skurka, Christine Cambareri, Cynthia Chauhan, Ana Barac
来源: Experimental Hematology & Oncology

摘要:

心力衰竭和癌症仍然是发病和死亡的两个主要原因,并且这两种疾病以复杂的方式相互关联。癌症患者发生与癌症治疗相关的心血管并发症的风险增加。新诊断癌症的患者出现心肌病或心力衰竭预示着不良肿瘤和心血管结局的高风险。随着癌症疗法的快速发展,其中许多疗法会干扰心血管稳态,心力衰竭从业者需要熟悉心脏肿瘤学的预防、风险分层、诊断和管理策略。美国心力衰竭协会的这份声明解决了癌症诊断活跃患者和癌症幸存者心力衰竭护理的复杂性。介绍了 A 至 D 期心力衰竭的心脏毒性风险分层、监测和管理,重点讨论了射血分数保留的心力衰竭和特殊人群,例如儿童和青年期癌症幸存者。我们概述了癌症和心力衰竭之间的共同危险因素,强调心力衰竭是与许多不同癌症治疗相关的心脏毒性的一种形式。最后,我们讨论了癌症和心脏病患者护理方面的差异,并提出了一个多学科团队方法框架,以及心力衰竭、肿瘤科、姑息治疗、药房和护理团队之间在管理这些复杂患者方面的关键合作。版权© 2024。由爱思唯尔公司出版。
Heart failure and cancer remain two of the leading causes of morbidity and mortality and the two disease entities are linked in a complex manner. Patients with cancer are at increased risk of cardiovascular complications related to the cancer therapies. The presence of cardiomyopathy or heart failure in a patient with new cancer diagnosis portends a high risk for adverse oncology and cardiovascular outcomes. With the rapid growth of cancer therapies, many of which interfere with cardiovascular homeostasis, heart failure practitioners need to be familiar with prevention, risk stratification, diagnosis, and management strategies in cardio-oncology. This Heart Failure Society of America statement addresses the complexities of heart failure care among patients with active cancer diagnosis and cancer survivors. Risk stratification, monitoring, and management of cardiotoxicity are presented across Stages A through D heart failure, with focused discussion on heart failure preserved ejection fraction and special populations such as survivors of childhood and young adulthood cancers. We provide an overview of the shared risk factors between cancer and heart failure, highlighting heart failure as a form of cardiotoxicity associated with many different cancer therapeutics. Finally, we discuss disparities in the care of patients with cancer and cardiac disease and present a framework for a multidisciplinary team approach and critical collaboration between heart failure, oncology, palliative care, pharmacy, and nursing teams in the management of these complex patients.Copyright © 2024. Published by Elsevier Inc.