在所有种族和族裔群体中，黑人女性的卵巢癌生存率是最低的。不良的饮食质量也对黑人群体产生了不成比例的影响，但其与该人群卵巢癌生存的关系在很大程度上仍不清楚。为了检查被诊断患有上皮性卵巢癌（EOC）的黑人女性的饮食模式与生存之间的关系。这项前瞻性队列研究在2010 年 12 月至 2015 年 12 月期间，在非裔美国人癌症流行病学研究 (AACES) 中，自我认定年龄为 20 至 79 岁的黑人女性新诊断出患有组织学确诊的 EOC，随访至 2022 年 10 月。AACES 是一项基于人群的卵巢研究美国 11 个地区黑人女性的癌症风险和生存率。数据分析时间为 2023 年 3 月至 2024 年 6 月。饮食模式通过 2020 年健康饮食指数 (HEI-2020) 和 2010 年替代健康饮食指数 (AHEI-2010) 进行评估，并根据前一年的饮食摄入量计算分数诊断并通过经过验证的 Block 2005 食物频率调查问卷收集。分数越高表明饮食质量越好。根据多变量 Cox 模型估计了所有参与者和高级别浆液性卵巢癌 (HGSOC) 患者中遵守饮食建议与总体死亡率之间关系的风险比 (HR) 和 95% CI。 483 名患有 EOC 的黑人女性（平均 [SD] 年龄，58.1 [10.5] 岁）在中位 (IQR) 4.3 (2.0-8.2) 年随访期间记录了 310 例死亡。总体而言，患有 EOC 的女性中没有发现饮食模式与死亡率之间存在关联。然而，在 325 名患有 HGSOC 的女性中，与第一个四分位数相比，更好地遵守 HEI-2020 与后四分位数的死亡率降低相关（HR，0.63；95% CI，四分位数 2 为 0.44-0.92；HR，0.67；95% CI ，四分位数 3 为 0.46-0.97；HR，0.63；95% CI，四分位数 4 为 0.44-0.91）。与四分位数 1 相比，AHEI-2010 在 HGSOC 女性的第二个四分位数（HR，0.62；95% CI，0.43-0.89）和第四个四分位数（HR，0.67；95% CI，0.45-0.98）中观察到类似的结果。在这项研究中，与诊断前饮食质量最低的女性相比，诊断前饮食质量中等和较高的女性的 HGSOC 死亡率显着降低。这些发现表明，即使在诊断前适度遵守饮食指南也可能与患有 HGSOC（最致命的卵巢癌）的黑人女性的生存率提高有关。

Ovarian cancer survival among Black women is the lowest across all racial and ethnic groups. Poor dietary quality also disproportionately affects Black populations, but its association with ovarian cancer survival in this population remains largely unknown.To examine associations between dietary patterns and survival among Black women diagnosed with epithelial ovarian cancer (EOC).This prospective cohort study was conducted among self-identified Black women aged 20 to 79 years newly diagnosed with histologically confirmed EOC in the African American Cancer Epidemiology Study (AACES) between December 2010 and December 2015, with follow-up until October 2022. AACES is a population-based study of ovarian cancer risk and survival among Black women in 11 US regions. Data were analyzed from March 2023 to June 2024.Dietary patterns were assessed by the Healthy Eating Index-2020 (HEI-2020) and Alternative Healthy Eating Index-2010 (AHEI-2010), with scores calculated based on dietary intake in the year prior to diagnosis and collected via the validated Block 2005 Food Frequency Questionnaire. Higher scores indicate better dietary quality.Hazard ratios (HRs) and 95% CIs were estimated from multivariable Cox models for the association between adherence to dietary recommendations and overall mortality among all participants and those with high-grade serous ovarian cancer (HGSOC).Among 483 Black women with EOC (mean [SD] age, 58.1 [10.5] years), 310 deaths were recorded during a median (IQR) follow-up of 4.3 (2.0-8.2) years. No association of dietary patterns with mortality was found among women with EOC overall. However, among 325 women with HGSOC, better adherence to HEI-2020 was associated with decreased mortality in later quartiles compared with the first quartile (HR, 0.63; 95% CI, 0.44-0.92 for quartile 2; HR, 0.67; 95% CI, 0.46-0.97 for quartile 3; HR, 0.63; 95% CI, 0.44-0.91 for quartile 4 ). Similar results were observed with AHEI-2010 among women with HGSOC for the second (HR, 0.62; 95% CI, 0.43-0.89) and fourth (HR, 0.67; 95% CI, 0.45-0.98) quartiles compared with quartile 1.In this study, women with moderate and high prediagnosis dietary quality had significantly lower mortality rates from HGSOC compared with women with the lowest prediagnosis dietary quality. These findings suggest that even moderate adherence to dietary guidelines prior to diagnosis may be associated with improved survival among Black women with HGSOC, the most lethal form of ovarian cancer.