海藻衍生的生物活性物质如多糖已被证明是有效的化疗和化学预防剂。海带多糖和藻酸盐的抗氧化特性通过细胞凋亡动态调节关键的细胞内信号通路，从而产生低细胞毒性和潜在的化疗效果，从而有助于预防癌症。了解昆布多糖和藻酸盐对人类癌细胞的影响及其在细胞死亡途径中的分子作用可以帮助开发一种新的化学预防策略。本综述强调了调亡昆布多糖和藻酸盐在一系列恶性肿瘤中的重要性以及它们的提取、分子结构和重量。此外，还讨论了未来纳米制剂的增强以提高临床疗效。海带多糖和海藻酸盐是完美的成分，因为它们具有独特的理化和生物学特性，以及它们在癌症中的基于用途的递送系统。昆布多糖和海藻酸盐抗癌的有效性以及更多的临床前和临床试验将作为新的化疗天然药物开放，从而被确立为潜在的癌症药物。版权所有 © 2024。由 Elsevier B.V. 出版。

Seaweed-derived bioactive substances such as polysaccharides have proven to be effective chemotherapeutic and chemopreventive agents. Laminarin and alginate antioxidant properties aid in the prevention of cancer through dynamic modulation of critical intracellular signaling pathways via apoptosis which produce low cytotoxicity and potential chemotherapeutic effects. Understanding the effects of laminarin and alginate on human cancer cells and their molecular roles in cell death pathways can help to develop a novel chemoprevention strategy. This review emphasizes the importance of apoptosis-modulating laminarin and alginate in a range of malignancies as well as their extraction, molecular structure, and weight. In addition, future nano-formulation enhancements for greater clinical efficacy are discussed. Laminarin and alginate are perfect ingredients because of their distinct physicochemical and biological characteristics and their use-based delivery systems in cancer. The effectiveness of laminarin and alginate against cancer and more preclinical and clinical trials will open up as new chemotherapeutic natural drugs which lead to established as potential cancer drugs.Copyright © 2024. Published by Elsevier B.V.