重新访问的四环素：皮肤科领域的四环素
Tetracyclines Revisited: Tetracyclines in the Field of Dermatology
影响因子:2.70000
分区:医学3区 / 皮肤病学3区
发表日期:2024
作者:
Yoon-Seob Kim, Hei Sung Kim
摘要
四环素是皮肤科医生青睐的一类广谱抗生素。在过去的十年中，四环素的临床疗效已扩展为各种皮肤病。该评论试图涵盖皮肤病学领域中四环素的可能指征和可能的作用机理。 This comprehensive review encompasses all possible indications of tetracyclines besides acne vulgaris and rosacea: hidradenitis suppurativa, autoimmune bullous dermatoses, vitiligo, alopecia, prurigo pigmentosa, granulomatous dermatoses, Kaposi's sarcoma, cold urticaria, atopic dermatitis, scrub typhus, scarring, and其他皮肤病。我们还专注于最近批准的sarecycline，第三代狭窄的四环素及其临床功效和对微生物组的潜在影响。我们的综述提供了对这种非常熟悉的药物类别的更好理解，并鼓励其在更广泛的皮肤病学疾病和症状中使用。这项研究全面回顾了有关皮肤病领域四环素的潜在指示的当前文献。
Abstract
Tetracyclines are a class of broad-spectrum antibiotics favored by dermatologists. Over the last decade, the clinical efficacy of tetracyclines has expanded into various dermatoses.This review tries to encompass the possible indications of tetracycline in the field of dermatology and possible mechanisms of action. This comprehensive review encompasses all possible indications of tetracyclines besides acne vulgaris and rosacea: hidradenitis suppurativa, autoimmune bullous dermatoses, vitiligo, alopecia, prurigo pigmentosa, granulomatous dermatoses, Kaposi's sarcoma, cold urticaria, atopic dermatitis, scrub typhus, scarring, and miscellaneous dermatoses. We also focus on the recently approved sarecycline, a third-generation narrow-spectrum tetracycline, and its clinical efficacy and potential impact on the microbiome. Our review provides a better understanding of this extremely familiar drug class and encourages its use in a wider spectrum of dermatologic diseases and symptoms.This study comprehensively reviewed the current literature on potential indications of tetracyclines in the field of dermatology.