由于大量研究报道了辐射引起的心脏事件，心脏肿瘤学最近受到了越来越多的关注。有鉴于此，目前的文献综述旨在涵盖过去 15 年的所有研究，以评估由于治疗演变而导致的心脏剂量变化，以及治疗计划习惯的变化，不仅将心脏作为一个整体还有心脏的亚结构。对于所有评估的肿瘤部位，现代治疗技术，特别是质子治疗，与更成熟的放射治疗相比，可以提供更好的心脏保护。强度调制，特别是与呼吸门控相结合，显示出与心脏相关的剂量体积参数的显着改善。虽然过去的研究认为平均心脏剂量是心脏毒性的唯一参考，但在计划期间对其他心脏亚结构进行剂量学评估的建议正变得越来越普遍。版权所有 © 2024 Elsevier B.V. 保留所有权利。

Cardio-oncology is lately gaining more attention due to radiation-induced cardiac events reported by a very large number of studies. In view of this, the current overview of the literature aimed to encompass all studies from the past 15 years to assess changes in cardiac dose due to treatment evolution, as well as the changes in treatment planning customs to incorporate not only the heart as a whole but also cardiac substructures. Modern treatment techniques, particularly proton therapy, offers superior cardiac sparing compared to more established radiotherapy, for all evaluated tumor sites. Intensity modulation, particularly coupled with respiratory gating shows significant improvement in dose-volume parameters pertaining to the heart. While past studies considered mean heart dose as the only reference for cardiac toxicities, recommendations for the other cardiac substructures to be dosimetrically assessed during planning are becoming more common.Copyright © 2024 Elsevier B.V. All rights reserved.