服用来氟米特的患者出现空洞性肺类风湿结节:病例报告。
Cavitary pulmonary rheumatoid nodules in a patient on leflunomide: A case report.
发表日期:2024 Dec
作者:
Abidou Kawélé Coulibaly, Imen Henchiri, Marine Meunier, Bernadette Saint-Marcoux
来源:
Arthritis & Rheumatology
摘要:
类风湿性关节炎是一种慢性炎症性风湿性疾病,可引起关节外表现,特别是胸膜肺受累,是这种结缔组织疾病的第二大死亡原因。我们报告了一种罕见的 RA 肺部表现。患者年龄58岁,服用来氟米特进行RA随访,发现3个肺结节,尺寸分别为13mm、10mm和6mm,提出感染、肺转移和类风湿结节的诊断假设。类风湿性关节炎中挖掘出的肺部结节的诊断是在抽吸其中一个结节后做出的,这排除了感染和癌性原因。这些结节在停止来氟米特 6 个月后消退。© 2024 作者。由爱思唯尔公司代表华盛顿大学出版。
Rheumatoid arthritis is a chronic inflammatory rheumatic disease that can cause extra-articular manifestations, in particular pleuropulmonary involvement, which is the second leading cause of death in this connective tissue disease. We report a rare pulmonary manifestation of RA. This was a 58-year-old patient being followed for RA on leflunomide with 3 excavated pulmonary nodules measuring 13 mm, 10 mm and 6 mm, for which the diagnostic hypotheses of infection, pulmonary metastases and rheumatoid nodules had been put forward. The diagnosis of excavated pulmonary nodules in rheumatoid arthritis was made after aspiration of one of the nodules, which ruled out infectious and cancerous causes. These nodules regressed 6 months after leflunomide was stopped.© 2024 The Authors. Published by Elsevier Inc. on behalf of University of Washington.