黄芪药食两用治疗胃肠道肿瘤的研究进展。
Research Progress in the Medicine-Food Dual Use of Astragalus for Gastrointestinal Tumors.
发表日期:2024 Oct 21
作者:
Jiaqing Li, Yang Niu, Ling Yuan, Wenjie Jiang, Taiqiang Jiao, Hongli Dou, Yi Nan
来源:
Food & Function
摘要:
胃肠道肿瘤对人类预期寿命和生活质量有重大影响,也是个人和社会卫生压力的主要原因。胃肠道肿瘤是癌症相关死亡的主要原因,主要治疗方法是手术、放疗和化疗。但它们对身体的损伤也很大,术后预后较差。因此,我们迫切需要安全有效的药物来干预胃肠道肿瘤。近年来,中医药作为补充和替代疗法被广泛应用于肿瘤治疗。黄芪是具有滋补作用的主要中药材之一,也是多种抗肿瘤中药复方的重要成分之一。黄芪多糖、皂苷、黄酮类化合物是黄芪的主要活性成分,均具有抗肿瘤作用。本文对近年来黄芪及其活性成分干预胃肠道肿瘤的作用机制进行了研究,并从药食同源的角度为黄芪干预胃肠道肿瘤的研究提出了新的思路。
Gastrointestinal tumors have a major impact on human life expectancy and quality of life and are a major cause of personal and social hygiene stress. Gastrointestinal tumors are the main cause of cancer-related death, and the main treatment methods are surgery, radiotherapy, and chemotherapy. However, they also cause great damage to the body and have a poor prognosis after surgery. Therefore, we urgently need safe and effective drugs to intervene in gastrointestinal tumors. In recent years, Traditional Chinese Medicine has been widely used in tumor treatment as a complementary and alternative therapy. Astragalus membranaceus is one of the main herbal medicines with tonic effect and one of the important components of many antitumor herbal compounds. Astragalus polysaccharides, saponins, and flavonoids are the main active components of Astragalus, all of which have antitumor effects. In this article, we studied the mechanism of action of Astragalus and its active ingredients in the intervention of gastrointestinal tumors in recent years and suggested a new approach for the study of Astragalus intervention in gastrointestinal tumors from the perspective of the homology of medicine and food.