放射治疗是用于头颈癌患者的一种治疗方式。它对粘合剂的粘合强度有负面影响。关于放射治疗对乳牙粘合剂粘合强度影响的信息很少。因此，这项体外研究旨在检测最佳的粘合系统和在受辐射的乳牙中应用修复体的粘合剪切粘合强度的理想时间。根据修复体应用时间和辐射暴露，将乳牙的牙本质样本随机分配到四组，（ G1：对照，G2：辐射前，G3：辐射后24小时，G4：辐射后6个月），每组20个样本。根据所使用的粘合剂系统，这些组进一步分为2个亚组，每个亚组10个样品。 (1) 3M™ 单键通用粘合剂 (SB)，(2) 3M AdperSingle Bond 2 (AS)。样品暴露在钴 60 机器的伽马辐射下。发射了一剂 60 Gy 的辐射。然后对样品进行剪切粘合强度测试。施加负载直至失效并记录最大负载。数值数据以平均值和标准差值表示，然后根据 Shapiro-Wilk 检验或 Levene 检验进行分布，并通过双向方差分析进行分析。所有测试的显着性水平均设置为 p<<0.05。使用 Windows 版 R 统计分析软件 4.4.1 版进行统计分析（Team RC，R：统计计算的语言和环境。R 统计计算基础，2023）。与 AS 亚组相比，SB 亚组表现出明显更高的值（p < 0.001）。对于SB，G1和G4组之间没有显着差异(p > 0.001)。然而，G1、G2 和 G3 之间存在显着差异（分别为 p < 0.001、P = 0.025、P = 0.265 ns），并且 G3 呈现最低值。对于AS，G1组和G4组之间没有显着差异（p =  < 0.001）。与其他组相比，G3 表现出显着差异（p = 0.265 ns）且结果最低。辐射后 24 小时进行的修复体的粘合强度低于辐射后 6 个月进行的修复体。无论使用哪种粘合剂系统，SB 在剪切粘合强度方面都比 AS 表现更好。© 2024。作者。

Radiotherapy is a treatment modality used for head and neck cancer patients. It has a negative influence on bonding strength of adhesives. Little information is available about the effect of radiotherapy on bonding strength of adhesives in primary teeth. Therefore, this in vitro study aimed to detect the best adhesive system and ideal time to apply restorations in primary irradiated teeth regarding adhesive shear bond strength.Dentin samples from primary teeth were randomly assigned to four groups based on restoration application time and radiation exposure, (G1: control, G2: preradiation, G3: 24 h postradiation, and G4: 6 months postradiation) with 20 samples per group. These groups were further divided into 2 subgroups according to the adhesive system used, with 10 samples per subgroup. (1) 3M™ Single Bond Universal Adhesive (SB), (2) 3M AdperSingle Bond 2 (AS). Samples were exposed to gamma radiation from a cobalt-60 machine. One shot of 60 Gy of radiation was delivered. Then samples were subjected to a shear bond strength test. The load was applied until failure and the maximum load was recorded. Numerical data are presented as mean and standard deviation values, then distributed according to Shapiro-Wilk test or Levene's test and analyzed via two-way ANOVA. The significance level was set at p < 0.05 for all tests. Statistical analysis was performed with R statistical analysis software version 4.4.1 for Windows (Team RC, R: A language and environment for statistical computing. R foundation for statistical computing, 2023).Compared with the AS subgroup, the SB subgroup presented significantly greater values (p < 0.001). For SB, there was no significant difference among the G1 and G4 groups (p > 0.001). However, there was a significant difference between G1, G2, and G3 (p < 0.001, P = 0.025, P = 0.265 ns respectively), and G3 presented the lowest values. For AS, there was no significant difference between groups G1 and G4 (p =  < 0.001). Compared with the other groups, G3 presented a significant difference (p = 0.265 ns) and the lowest results.Restorations performed 24 h after radiation had lower bond strength than those performed six months after radiation. Regardless of the adhesive system used, SB performed better than AS in terms of the shear bond strength.© 2024. The Author(s).