电离辐射对初级牙齿两种不同粘合剂系统的剪切键强度的影响。体外研究

放射疗法是用于头颈癌患者的治疗方式。它对粘合剂的粘结强度有负面影响。关于放射疗法对原发牙粘合剂粘结强度的影响的信息很少。 Therefore, this in vitro study aimed to detect the best adhesive system and ideal time to apply restorations in primary irradiated teeth regarding adhesive shear bond strength.Dentin samples from primary teeth were randomly assigned to four groups based on restoration application time and radiation exposure, (G1: control, G2: preradiation, G3: 24 h postradiation, and G4: 6 months postradiation) with 20 samples per group.根据所使用的粘合剂系统将这些组进一步分为2个亚组，每个亚组有10个样品。 （1）3M™单键通用粘合剂（SB），（2）3M AdperSingle键2（AS）。将样品暴露于钴60机器中的伽马辐射中。交付了60 Gy辐射的一枪。然后对样品进行剪切键强度测试。施加负载直到失败并记录最大负载。数值数据表示为平均值和标准偏差值，然后根据Shapiro-Wilk检验或Levene的测试分布，并通过双向方差分析进行分析。对于所有测试，显着性水平设置为p <0.05。使用R统计分析软件4.4.1的Windows进行统计分析（Team RC，R：用于统计计算的语言和环境。R统计计算基础，2023年）。与AS子组相关，SB子组的值显着更大（P <0.001）。对于SB，G1和G4组之间没有显着差异（P> 0.001）。但是，G1，G2和G3之间存在显着差异（p <0.001，p = 0.025，p = 0.265 ns），而G3的值最低。对于AS，G1和G4组之间没有显着差异（P = <0.001）。与其他组相比，G3呈显着差异（P = 0.265 ns），结果最低。辐射后24小时进行的放射强度低于辐射后六个月进行的键强度。无论使用哪种粘合剂系统，SB的性能都比剪切键强度更好。

Radiotherapy is a treatment modality used for head and neck cancer patients. It has a negative influence on bonding strength of adhesives. Little information is available about the effect of radiotherapy on bonding strength of adhesives in primary teeth. Therefore, this in vitro study aimed to detect the best adhesive system and ideal time to apply restorations in primary irradiated teeth regarding adhesive shear bond strength.Dentin samples from primary teeth were randomly assigned to four groups based on restoration application time and radiation exposure, (G1: control, G2: preradiation, G3: 24 h postradiation, and G4: 6 months postradiation) with 20 samples per group. These groups were further divided into 2 subgroups according to the adhesive system used, with 10 samples per subgroup. (1) 3M™ Single Bond Universal Adhesive (SB), (2) 3M AdperSingle Bond 2 (AS). Samples were exposed to gamma radiation from a cobalt-60 machine. One shot of 60 Gy of radiation was delivered. Then samples were subjected to a shear bond strength test. The load was applied until failure and the maximum load was recorded. Numerical data are presented as mean and standard deviation values, then distributed according to Shapiro-Wilk test or Levene's test and analyzed via two-way ANOVA. The significance level was set at p < 0.05 for all tests. Statistical analysis was performed with R statistical analysis software version 4.4.1 for Windows (Team RC, R: A language and environment for statistical computing. R foundation for statistical computing, 2023).Compared with the AS subgroup, the SB subgroup presented significantly greater values (p < 0.001). For SB, there was no significant difference among the G1 and G4 groups (p > 0.001). However, there was a significant difference between G1, G2, and G3 (p < 0.001, P = 0.025, P = 0.265 ns respectively), and G3 presented the lowest values. For AS, there was no significant difference between groups G1 and G4 (p =  < 0.001). Compared with the other groups, G3 presented a significant difference (p = 0.265 ns) and the lowest results.Restorations performed 24 h after radiation had lower bond strength than those performed six months after radiation. Regardless of the adhesive system used, SB performed better than AS in terms of the shear bond strength.